Old-old-school Italian place Little Joe's (85 5th Street at Mission) has known quite a few locations around town since its original Columbus Avenue incarnation in North Beach. They moved first up to Broadway, then to Van Ness, and then in 2007 to their current location at 5th and Mission. Now the owners tell Grub Street that the lease came up it is time to move again, this time to 1106 Market Street, at the base of the Renoir Hotel at 7th and Market Street not quite as tourist- and convention-friendly as Fifth and Mission, but everyone keeps saying the neighborhood's looking up! The space has played host to several short-lived ventures, most recently Neptalia and Cafe do Brazil (it's also next door to what will soon become a nightclub called Fuel). Little Joe's hopes to complete their move within a few weeks, pending some remodeling and inspections. Mid-Market has been sorely in need of some eggplant parmigiano... [Grub Street] Update: Little Joe's on 5th has now closed, and word has it there's another "better" Italian place taking its place shortly.